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cephalosporin |
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cephalosporinAny of a class of broad-spectrum antibiotics derived from a fungus (genus Cephalosporium). They are similar to penicillins and are used on penicillin-resistant infections. The first cephalosporin was extracted from sewage-contaminated water, and other naturally occurring ones have been isolated from moulds taken from soil samples. Side effects include allergic reactions and digestive upsets. Synthetic cephalosporins can be designed to be effective against a particular pathogen. |
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| Ceftobiprole is the first anti-MRSA broad-spectrum cephalosporin to demonstrate efficacy in a large clinical trial in patients infected with staphylococcal infections, including methicillin-resistant Staphylococcus aureus (MRSA). Four patients with penicillin allergy were given clindamycin rather than a cephalosporin. With the approval of ceftriaxone, APP retains its position with the largest portfolio of anti-infectives in the generic injectables industry and its leadership position in the cephalosporin market. |
cephalosporin
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