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chloramphenicol

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chloramphenicol

The first broad-spectrum antibiotic to be used commercially. It was discovered in 1947 in a Venezuelan soil sample containing the bacillus Streptomyces venezuelae, which produces the antibiotic substance C11H12Cl2N2O5, now synthesized. Because of its toxicity, its use is mainly limited to the treatment of life-threatening infections, such as meningitis, legionnaire's disease, and typhoid fever.



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? Mentioned in ? References in periodicals archive
 
40,41) There are no conclusive data on CSF sterilization with ampicillin plus chloramphenicol or with other antibiotics that have been studied.
Do corticosteroids prevent hearing loss in pediatric bacterial ... by Johnson, Romaine / Ear, Nose and Throat Journal
Typhimurium isolates were identified as DT104, and all had a pentavalent resistance pattern (resistance to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline) (3).
Salmonella typhimurium DT104, Italy by Luzzi, Ida / Emerging Infectious Diseases
There has been less concern, internationally or nationally, over the potential public health risks associated with residues of growth promoters in meat products, although the discovery of chloramphenicol in Asian shrimp in 2002 resulted in a requirement that all shrimp be tested before sale in the EU (Delegation of the European Commission to Thailand 2002).
Arsenic in food by Silbergeld, Ellen K. / Environmental Health Perspectives
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