chromogranin - Hutchinson encyclopedia article about chromogranin Printer Friendly
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chromogranin

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chromogranin

Protein released by the adrenal gland, along with the hormone adrenaline, during times of stress. There are three types, chromagranin A, B, and C. The function of chromagranins is poorly understood, but they do have an antibacterial affect that could boost the immune system when it is suppressed during times of stress. Chromagranin A also stimulates insulin release and relaxes blood vessels - functions similarly reduced by adrenaline during stress.
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Clinical and demographic findings can help make distinctions, as can pertinent immunohistochemical reactions to synaptophysin, chromogranin, neuron-specific enolase (NSE), neurofilament protein (NFP), S-100 protein, keratin, CD45RB, desmin, CD99, and HMB45.
Olfactory neuroblastoma by Thompson, Lester D.R. / Ear, Nose and Throat Journal
Immunohistochemical staining for $100 was performed to characterize malignant schwannoma, whereas chromogranin A staining was used to characterize olfactory neuroblastomas.
First experimental demonstration of the multipotential carcinogenic ... by Rigano, Anna / Environmental Health Perspectives
In such a setting, immunohistochemistry analysis will help with the separation between primary and metastatic tumors: primary thyroid follicular tumors will usually be immunoreactive with thyroglobutin, CK7, and TTF-1, while C-cell--derived tumors will be reactive to calcitonin and chromogranin.
Neoplasms metastatic to the thyroid gland by Thompson, Lester D.R. / Ear, Nose and Throat Journal
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