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anticoagulant
(redirected from circulating anticoagulant)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.01 sec.

anticoagulant

Substance that inhibits the formation of blood clots. Common anticoagulants are heparin, produced by the liver and some white blood cells, and derivatives of coumarin, such as warfarin. Anticoagulants are used medically in the prevention and treatment of thrombosis and heart attacks. Anticoagulant substances are also produced by blood-feeding animals, such as mosquitoes, leeches, and vampire bats, to keep the victim's blood flowing.

Most anticoagulants prevent the production of thrombin, an enzyme that induces the formation from blood plasma of fibrinogen, to which blood platelets adhere and form clots.



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? Mentioned in ? References in periodicals archive
 
  a circulating anticoagulant that inhibits the conversion of prothrombin to thrombin; it paradoxically increases the risk of thromboembolism and is seen in some cases of systemic lupus erythematosus.
  a circulating anticoagulant that inhibits the conversion of prothrombin to thrombin; it paradoxically increases the risk of thromboembolism and is seen in some cases of systemic lupus erythematosus.
  a circulating anticoagulant that inhibits the conversion of prothrombin to thrombin; it paradoxically increases the risk of thromboembolism and is seen in some cases of systemic lupus erythematosus.
 
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