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cleavage
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cleavage

In geology and mineralogy, the tendency of a rock or mineral to split along defined, parallel planes related to its internal structure; the clean splitting of slate is an example. It is a useful distinguishing feature in rock and mineral identification. Cleavage occurs as a result of realignment of component minerals during deformation or metamorphism. It takes place where bonding between atoms is weakest, and cleavages may be perfect, good, or poor, depending on the bond strengths; a given rock or mineral may possess one, two, three, or more orientations along which it will cleave.

Some minerals have no cleavage, for example, quartz will fracture to give curved surfaces similar to those of broken glass. Some other minerals, such as apatite, have very poor cleavage that is sometimes known as a parting. Micas have one perfect cleavage and therefore split easily into very thin flakes. Pyroxenes have two good cleavages and break (less perfectly) into long prisms. Galena has three perfect cleavages parallel to the cube edges, and readily breaks into smaller and smaller cubes. Baryte has one perfect cleavage plus good cleavages in other orientations.


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The acquisition of a highly cleavable HA converted an avirulent strain to virulence in Pennsylvania in 1983 (H5N2), Mexico in 1994 (H5N2), Italy in 1997 (H7N1), Chile in 2002 (H7N3), and Canada in 2004 (H7N3) (Table).
SGN-35 is an ADC comprised of an anti-CD30 antibody joined by an enzyme cleavable linker to a potent, synthetic drug payload, monomethyl auristatin E (MMAE), using Seattle Genetics' proprietary technology.
SGN-35 is an ADC comprised of an anti-CD30 antibody linked by an enzyme cleavable peptide linker to an auristatin derivative, monomethyl auristatin E (MMAE), using Seattle Genetics' proprietary ADC technology.
 
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