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clot-buster| Popular term for a small group of thrombolytic (clot-dissolving) drugs used in the treatment of heart attack. See also streptokinase. |
| Tissue plasminogen activator (tPA) is a natural clot-buster found in the bloodstream. It prevents excess clotting and a synthetic version is used to diperse clots in heart attack victims. Premenopausal women have higher levels of TPA in their blood than men of the same age, but after menopause there is little difference in the levels. |
| TPA was approved by the US Food and Drug Administration (FDA) for the treatment of strokes caused by blood clots. |
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