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codon |
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codonIn genetics, a triplet of bases (see base pair) in a molecule of DNA or RNA that directs the placement of a particular amino acid during the process of protein (polypeptide) synthesis. As each of the three positions can be filled by any of the four bases, there are 43 = 64 codons in the genetic code. |
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| Amyloid protein of Gerstmann-Straussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58. Biologists have long held that swapping one codon for another doesn't change the resulting protein's structure, as long as both codons instruct the machinery to insert the same amino acid. The Sec residue in selenoproteins as GSH-Px and SeP is co-translationally incorporated via a predefined UGA codon, which has a specific covalent binding capacity. |
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