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corticosteroid |
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corticosteroidAny of several steroid hormones secreted by the cortex of the adrenal glands; also synthetic forms with similar properties. Corticosteroids have anti-inflammatory and immunosuppressive effects and may be used to treat a number of conditions, including rheumatoid arthritis, severe allergies, asthma, some skin diseases, and some cancers. Side effects can be serious, and therapy must be withdrawn very gradually. The two main groups of corticosteroids include glucocorticoids (cortisone, hydrocortisone, prednisone, and dexamethasone), which are essential to carbohydrate, fat, and protein metabolism, and to the body's response to stress; and mineralocorticoids (aldosterone, fluorocortisone), which control the balance of water and salt in the body. |
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| The randomized, double-blind, placebo-controlled clinical trial was designed to evaluate the efficacy and safety of MMF in maintaining or improving symptom control with reduced doses of corticosteroids in patients with myasthenia gravis over a treatment period of 36 weeks. Q Why are corticosteroids so often prescribed for autoimmune diseases, and what are their risks? Diabetes in patients with advanced disease can be long standing or associated with recent corticosteroid use. |
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