cosmid - Hutchinson encyclopedia article about cosmid Printer Friendly
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cosmid

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cosmid

Fragment of DNA, for example from the human genome, inserted into a bacterial cell. The bacterium replicates the fragment along with its own DNA. In this way the fragments are copied for a gene library. Cosmids are characteristically 40,000 base pairs in length. The most commonly used bacterium is Escherichia coli. A yeast artificial chromosome (YAC) works in the same way.


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Created with DNA from a bacteriophage (a virus that infectsbacteria) combined with genetic material called a cosmid from the common bacterium Escherichia coli, the shuttle phasmid can infect mycobacteria and grow in E.
erythraea was derived from 256 canonically ordered cosmid clones representing a circular genome of 8.
 
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