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cyclic AMP
(redirected from Cyclic adenosine monophosphate)

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cyclic AMP

Cyclic 3,5-adenosine monophosphate, a major communicator molecule in living cells. It is formed by the action of the enzyme adenyl cyclase on ATP and has many physiological functions. It plays a part in increasing the level of blood glucose. Adrenaline, which increases the level of blood sugar, does so by stimulating the production of cAMP. Cyclic AMP is also involved in the synthesis of flagellar proteins in bacteria, and in hormone release, urine regulation, and sensory and nerve processes. In some organisms, cAMP seems to be active in the breakdown of lipids for the production of energy, when glucose is unavailable.



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The mutation leads to a loss of guanosine triphosphatase activity and thus to adenyl cyclase overactivity and subsequent overproduction of cyclic adenosine monophosphate (cAMP).
Benowitz' team injected the animals' eyes with oncomodulin in slow-release capsules, along with a chemical called cyclic adenosine monophosphate that's known to prompt nerve cells to respond to other growth factors.
David Summers, "at a certain dose the drug simply shuts down SMC migration by elevating cyclic adenosine monophosphate (cAMP) which modulates the G-protein pathway arresting cell migration by causing dose-response retraction of the cells microtubule pods.
 
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