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cyclosporin

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cyclosporin

Immunosuppressive drug derived from a fungus (Tolypocladium inflatum). In use by 1978, it revolutionized transplant surgery by reducing the incidence and severity of rejection of donor organs.

It suppresses the T-cells (see lymphocyte) that reject foreign tissue without suppressing other cells that fight infection and cancer.



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Of course, the latter two therapies can lead to skin cancer, and many of the drugs used to treat the disease, including methotrexate and cyclosporin, also have serious side effects, including increased risk of cancer.
Women & skin health by National Women's Health Report
Immunosuppressive agents commonly used include Cyclosporin, Tacrolimus, Mycophenolate Mofetil and Azathioprine.
Organ and tissue transplantation: an Australian perspective by Williams, Jodie / Australian Nursing Journal
The text has an extensive list of substances currently being used as transdermal agents that are organized by drug class and include familiar drugs such as nicotine, fentanyl, cyclosporin, heparin, and estrogens.
Transdermal Drug Delivery, 2nd rev. ed by Marovino, Tiziano / Physical Therapy
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