cyclosporine - Hutchinson encyclopedia article about cyclosporine Printer Friendly
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cyclosporin
(redirected from cyclosporine)

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cyclosporin

Immunosuppressive drug derived from a fungus (Tolypocladium inflatum). In use by 1978, it revolutionized transplant surgery by reducing the incidence and severity of rejection of donor organs.

It suppresses the T-cells (see lymphocyte) that reject foreign tissue without suppressing other cells that fight infection and cancer.



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In test tubes, normally slow-growing lung cancer cells that were exposed to cyclosporine developed hallmarks typical of more aggressive cancer cells.
Transplant drug increases cancer risk by Science News
2% w/v, KeraKlear was found to be a clear solution, compared to emulsified Cyclosporine 0.
Lipicard's KeraKlear(R)- Clear Solution for Dry Eyes by Business Wire
Miller's own unpublished research, funded in part by MDA, suggests that cyclosporine temporarily improves muscle strength in boys with Duchenne's muscular dystrophy.
Muscular dystrophy: new focus on myoblasts by Fackelmann, Kathy A. / Science News
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