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cytochrome
(redirected from cytochrome system)

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cytochrome

Protein responsible for part of the process of respiration by which food molecules are broken down in aerobic organisms. Cytochromes are part of the electron transport chain, which uses energized electrons to reduce molecular oxygen (O2) to oxygen ions (O2–). These combine with hydrogen ions (H+) to form water (H2O), the end product of aerobic respiration. As electrons are passed from one cytochrome to another, energy is released and used to make ATP.



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17,27) If the fetal circulation becomes saturated with acetaminophen as a result of maternal overdose, oxidation of acetaminophen through the P450 cytochrome system may produce sufficient toxic intermediary to cause hepatic injury in the neonate.
The ability of CO to inhibit the cytochrome system accounts for the profound neurological depression that often continues beyond the time COHb levels have been reduced to below toxic concentrations.
The P450 2D6 structure is a milestone in ongoing work to determine the structures of various bound substrates and inhibitors related to ligand recognition and specificity in human cytochrome systems.
 
 
 
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