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cytochrome |
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cytochrome
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Most of the statins are metabolized by the CYP450 cytochrome system. The P450 2D6 structure is a milestone in ongoing work to determine the structures of various bound substrates and inhibitors related to ligand recognition and specificity in human cytochrome systems. 17,27) If the fetal circulation becomes saturated with acetaminophen as a result of maternal overdose, oxidation of acetaminophen through the P450 cytochrome system may produce sufficient toxic intermediary to cause hepatic injury in the neonate. |
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