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dissociation
(redirected from dissociation constant)

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dissociation

In chemistry, the process whereby a single compound splits into two or more smaller products, which may be capable of recombining to form the reactant.

Where dissociation is incomplete (not all the compound's molecules dissociate), a chemical equilibrium exists between the compound and its dissociation products. The extent of incomplete dissociation is defined by a numerical value (dissociation constant).


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Dan Sexton, investigator, Dyax Corporation, also spoke at the conference in a presentation entitled "A Microarray-Based Surface Plasmon Resonance Method for the Rapid Determination of Phage Display Derived Human Antibody Dissociation Constants.
Fit competition and sigmoidal dose-response equations to learn the affinity of the receptor for the competing molecule, EC50, or specify ligand concentration and Kd to generate Ki, the equilibrium dissociation constant.
 
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