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diuresis |
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diuresis
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| Clinical trials using sodium bicarbonate suggest that alkalising the diuresis helps prevent acute renal failure (ARF) in myoglobinuria, by preventing the breakdown of myoglobin into a substance toxic to the proximal tubules (Cunningham 1997). Although all urinary parameters were adjusted for CreatU, we performed multiple regression analyses by again testing CreatU levels to eliminate any residual effect of the diuresis. Intracranial pressure is reduced by hyperventilation, supplemented if necessary by mannitol diuresis or by the release of CSF through a tiny hole created in the temporal dura. |
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