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double blind trial

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double blind trial

In medicine, method often used in clinical trials of new medicines. Patients are placed in groups using a randomization code and each group receives a different treatment or a placebo. Neither the investigator nor the patient knows which treatment is being administered during the trial. The randomization code is broken at the end of the trial and the results are analysed statistically. Double blind trials eliminate bias but they must be rigorously controlled using recognized ethical standards.



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In a double blind trial of 809 adults with osteoarthritis, patients were randomized to one of four different groups--placebo, rofecoxib 12.
Primary Care Based Randomised, Double Blind Trial of Amoxicillin Versus Placebo for Acute Otitis Media in Children Aged under 2 Years," British Medical Journal 320 (February 5, 2000): 350-354.
Altus' Phase II study is the largest prospective, randomized, double blind trial ever conducted to evaluate the safety and efficacy of enzyme replacement therapy in the treatment of patients with pancreatic insufficiency.
 
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