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shock |
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shockIn medicine, circulatory failure marked by a sudden fall of blood pressure and resulting in pallor, sweating, fast (but weak) pulse, and sometimes complete collapse. Causes include disease, injury, and psychological trauma. In shock, the blood pressure falls below that necessary to supply the tissues of the body, especially the brain. Treatment depends on the cause. Rest is needed, and, in the case of severe blood loss, restoration of the normal circulating volume. |
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| Despite the most modern of intensive life support measures, this means that 150,000 to 300,000 people die each year in the United States from endotoxic shock (sepsis) and it is estimated that the cost in treating these patients is $5 to $10 billion dollars, annually. Compounds such as CV1013 that can inhibit caspases may potentially form the basis for new drugs for endotoxic shock and other degenerative diseases. |
endotoxic shock
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