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erythroblast
(redirected from erythroblastic)

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erythroblast

In biology, a series of nucleated cells that go through various stages of development in the bone marrow until they form red blood cells (erythrocytes). This process is known as erythropoiesis. Erythroblasts can appear in the blood of people with blood cancers.



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1) ERBB2 is the official name provided by the HUGO Gene Nomenclature Committee for the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene that encodes a member of the epidermal growth factor receptor family of receptor tyrosine kinases.
We designed highly purified salt-free OliGold primers (Eurogentec, Seraing, Belgium) for the internal control gene hypoxanthine phosphoribosyhransferase 1 (HPRT1) and for target genes estrogen receptor-[alpha] (ESR1), progesterone receptor (PGR), PDZ domain containing 1 (PDZK1), and erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2) using Roche Lightcycler software (Roche Diagnostics Belgium, Vilvoorde, Belgium).
However, special stains later revealed atypical blasts negative for myeloperoxidase and positive for hemoglobin, consistent with erythroblastic origin.
 
 
 
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