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ex vivo

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ex vivo

Outside of the living body. In analogy to in vitro (in the test tube) and in vivo (in the living organism), ex vivo is used to describe procedures which involve removing cells, tissues, or organs from the living organism for treatment, manipulation, or analysis, and then returning them.

In gene therapy, for example, ex vivo describes a technique used in which genetically defective cells are removed and cultured in vitro. After growth, normal genes are added to the cells to correct the defect. These modified cells are next returned to the donor.



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Later chapters cover in vivo 1H MRS of breast tumors, the role of MRS in imaging of auxiliary lymph nodes in breast cancer, and in vitro, ex vivo, and high-resolution magic-angle-spinning (HRMAS) MRS of breast tumors.
In human cells ex vivo, Oxifend Plus was shown to be a powerful antioxidant and protects the cells from oxidative stress equal to 2062 imol Trolox Equivalents/gram.
Under the protocol, patients will also receive autologous dendritic cells (DC) processed ex vivo in addition to the TCR-gene transduced PBMCs, that are expected to enable enhancement of patients' immunity to attack the melanoma cells.
 
 
 
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