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exon |
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exon
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Until recently, it was believed that only exonic sequences were functional, and that the rest of the DNA was a sort of genetic detritus, consisting of useless code such as defective copies of genes, nonsensical repeats, and the remains of disabled retroviruses (potent viruses such as HIV that can insinuate their code into the DNA of their hosts). Exonic point mutations in NADH cytochrome B5-reductase genes of homozygotes for hereditary methemoglobinemia, types I and III: putative mechanisms of tissue-dependent enzyme deficiency. Probe content for the new BeadChips is based on well-annotated sequence information derived largely from the Mouse Exonic Evidence-Based Oligonucleotide (MEEBO) consortium. |
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