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fibrin
(redirected from fibrinoid)

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fibrin

Insoluble protein involved in blood clotting. When an injury occurs fibrin is deposited around the wound in the form of a mesh, which dries and hardens, so that bleeding stops. Fibrin is developed in the blood from a soluble protein, fibrinogen.

The conversion of fibrinogen to fibrin is the final stage in blood clotting. Platelets, a type of cell found in blood, release the enzyme thrombin when they come into contact with damaged tissue, and the formation of fibrin then occurs. Calcium, vitamin K, and a variety of enzymes called factors are also necessary for efficient blood clotting.
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Histopathologic findings included a marked lympho-histiocytic fibrinoid necrotizing vasculitis affecting small blood vessels and arterioles in the kidney and liver (Figure) and associated with lymphocytic interstitial nephritis and mild multifocal granulomatous hepatitis.
Ovine herpesvirus 2 infection in foal, Brazil by Costa, Erica A.; Bomfim, Maria Rosa Q.; da Fonseca, Flavio G.; Drumond, Betania P.; Coelho, Fabiana / Emerging Infectious Diseases
Signs of fibrinoid necrosis, endothelial swelling and nuclear dust were detected.
Genital pyoderma gangrenosum associated with chronic lymphoblastic ... by Atzori, Laura; Pinna, Anna Luisa; Pilloni, Luca; Pau, Monica; Aste, Nicola / Archives: The International Journal of Medicine
plexiform lesions or fibrinoid necrosis of vessels were not observed in the obese or morbidly obese subjects (from Pulmonary and Cardiovascular Complications of Obesity-Haque et al) 4.
A Review of Articles From Last Month's Archives of Pathology & ... by Anonymous / Archives of Pathology & Laboratory Medicine
 
 
 
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