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fibrin |
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fibrinInsoluble protein involved in blood clotting. When an injury occurs fibrin is deposited around the wound in the form of a mesh, which dries and hardens, so that bleeding stops. Fibrin is developed in the blood from a soluble protein, fibrinogen. The conversion of fibrinogen to fibrin is the final stage in blood clotting. Platelets, a type of cell found in blood, release the enzyme thrombin when they come into contact with damaged tissue, and the formation of fibrin then occurs. Calcium, vitamin K, and a variety of enzymes called factors are also necessary for efficient blood clotting. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Vascular damages were endothelial swelling and vascular fibrinoid necrosis (Figure 2). Biopsy results positive for Winkler's disease include epithelial hyperplasia, collagen degeneration, focal fibrinoid necrosis, and inflammatory cells with or without cartilage degeneration. Fibrinoid necrosis of the vessel occurred often, and the tunica intima was frequently thickened. |
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