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epilepsy |
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epilepsyMedical disorder characterized by a tendency to develop fits, which are convulsions or abnormal feelings caused by abnormal electrical discharges in the cerebral hemispheres of the brain. Epilepsy can be controlled with a number of anticonvulsant drugs. The term epilepsy covers a range of conditions from mild ‘absences’, involving momentary loss of awareness, to major convulsions. In some cases the abnormal electrical activity is focal (confined to one area of the brain); in others it is generalized throughout the cerebral cortex. Fits are classified according to their clinical type. They include: the grand mal seizure with convulsions and loss of consciousness; the fleeting absence of awareness petit mal, almost exclusively a disorder of childhood; Jacksonian seizures, originating in the motor cortex; and temporal-lobe fits, which may be associated with visual hallucinations and bizarre disturbances of the sense of smell. Epilepsy affects 1–3% of the world's population. It may arise spontaneously or may be a consequence of brain surgery, organic brain disease, head injury, metabolic disease, alcoholism, or withdrawal from some drugs. Almost a third of patients have a family history of the condition. Most epileptics have infrequent fits that have little impact on their daily lives. Epilepsy does not imply that the sufferer has any impairment of intellect, behaviour, or personality. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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This procedure may be performed in individuals who have focal epilepsy, where the site of seizure generation is in a single, well-identified area that can be excised without major risk of neurological deficits. For patients with drug-resistant focal epilepsy, surgery is an increasingly common alternative and MEG is proving useful for locating epileptogenic zones in relation to other functionally important areas of the brain. Edwards' research with epilepsy patients has determined a measurement of marginal predictability (MP) of seizure onset derived from scalp electroencephalogram recordings; further, they determined significant, consistent changes in MP several tens of minutes prior to a seizure in patients with focal epilepsy. |
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