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| We also note that Zn produces a more profound effect on the accumulation of mRNAs coding for several potassium channels, a cardiac calcium channel, and a gap junction protein, indicating that Zn may precipitate an electrical remodeling process in the heart. The two researchers discovered that cell-to-cell portals known as gap junctions are required for proper left-right patterning. They stated that autosomal-recessive mutations in the gap junction protein connexin 26 gene are responsible for 20% of all childhood hearing loss, with a carrier rate of 0. |
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