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nitroglycerine |
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nitroglycerineFlammable, explosive oil produced by the action of nitric and sulphuric acids on glycerol. Although poisonous, it is used in cardiac medicine. It explodes with great violence if heated in a confined space and is used in the preparation of dynamite, cordite, and other high explosives. It was synthesized by the Italian Ascanio Soberro in 1846, and is unusual among explosives in that it is a liquid. Nitroglycerine is an effective explosive because it has low activation energy, and produces little smoke when burned. However, it was initially so reactive it was virtually unusable. Alfred Nobel's innovation was to purify nitroglycerine (using water, with which it is immiscible, to dissolve the impurities), and thereby make it more stable, and absorb it into wood flour to make dynamite. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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An angina diary was kept for a week, recording episodes of angina (including length and severity) and number of treatments with glyceryl trinitrate (GTN) required. GISSI-3, entitled "Effects of lisinopril and transdermal glyceryl trinitrate singly and together on six-week mortality and vertricular function after acute myocardial infarction" and published in The Lancet on May 7, 1994, is the first trial to evaluate the short-term effects of administering lisinopril within the first 24 hours after a heart attack. Intravenous glyceryl trinitrate (GTN) at less than 100mcg/min or as negotiated by nursing/medical staff; |
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