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castration |
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castrationRemoval of the sex glands (either ovaries or testes). Male domestic animals may be castrated to prevent reproduction, to make them larger or more docile, or to eradicate disease. Castration of humans was used in ancient and medieval times and occasionally later to preserve the treble voice of boy singers or, by Muslims, to provide eunuchs, trustworthy harem guards. If done in childhood, it inhibits sexual development: for instance, the voice remains high, and growth of hair on the face and body is reduced, owing to the absence of the hormones normally secreted by the testes.
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Gonadectomy before CB3 infection reduces myocarditis in female (Figure 6A) and male mice (Figure 6B). Sex differences in response rates during random-ratio acquisition: effects of gonadectomy. Gonadal hormones appear to provide a tonic inhibitory function on the thymus; gonadectomy in adulthood leads to an increase in thymic tissue, whereas estrogen can produce thymic involution. |
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