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histamine |
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histamineInflammatory substance normally released in damaged tissues, which also accounts for many of the symptoms of allergy. It is an amine, C5H9N3. Substances that neutralize its activity are known as antihistamines. Histamine was first described in 1911 by British physiologist Henry Dale (1875–1968). How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Anatomic distribution of receptors (25-37) Area Receptor postrema PCRF/NTS AMPA/NMDA + + Muscarinic + + Histaminic [H. However, in pre-clinical studies, Serlect was demonstrated to be a potent antagonist at dopamine D2-, serotonin 5HT2-, and alpha1-receptors without activity at histaminic H1 or muscarinic receptors. As demonstrated in pre-clinical studies, sertindole is a potent antagonist at D2, 5HT2 and alpha1 receptors without activity at histaminic, muscarinic or alpha2 receptors. |
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