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jaundice |
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jaundiceYellow discoloration of the skin and whites of the eyes caused by an excess of bile pigment in the bloodstream. Approximately 60% of newborn babies exhibit some degree of jaundice, which is treated by bathing in white, blue, or green light that converts the bile pigment bilirubin into a water-soluble compound that can be excreted in urine. A serious form of jaundice occurs in rhesus disease (see rhesus factor). Bile pigment is normally produced by the liver from the breakdown of red blood cells, then excreted into the intestines. A build-up in the blood is due to abnormal destruction of red cells (as in some cases of anaemia), impaired liver function (as in hepatitis), or blockage in the excretory channels (as in gallstones or cirrhosis). The jaundice gradually recedes following treatment of the underlying cause. |
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| Physical examination disclosed mild icteric sclera and multiple ecchymoses on the extremities. These cases could not be distinguished from hepatitis C cases based on incubation period, but they tended to be clinically milder; none were icteric compared to 30% of HCV cases and the mean peak ALT was half that of HCV infections (302 U/L vs. During the icteric phase, patients may be viremic (2). |
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