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point
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point

In geometry, a basic element, whose position in the Cartesian system may be determined by its coordinates.

Mathematicians have had great difficulty in defining the point, as it has no size, and is only the place where two lines meet. According to the Greek mathematician Euclid, (i) a point is that which has no part; (ii) the straight line is the shortest distance between two points.



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Isoelectric focusing showed that AX476 produced a [beta]-lactamase with an isoelectric point of 7.
Separation can be done simply at the whole-protein level using two-dimensional gel electrophoresis; this technique separates molecules by molecular weight and isoelectric point (the pH at which a molecule carries no net electrical charge).
The mixed-mode sorbents can distinguish proteins that have similar or very close isoelectric points, a separation that cannot be achieved with a single ion exchange step.
 
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