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keratin |
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keratinFibrous protein found in the skin of vertebrates and also in hair, nails, claws, hooves, feathers, and the outer coating of horns. If pressure is put on some parts of the skin, more keratin is produced, forming thick calluses that protect the layers of skin beneath. |
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Microscopy of skin sections containing epidermis showed compact keratinization, parakeratotic foci, and irregular hyperplasia with a pseudoepitheliomatous area. According to the university's research group, the congenital abnormality of KRAS and BRAF induces CFC syndrome, a rare genetic disorder characterized by a distinctive facial appearance, congenital cardiac lesion, mental deficiency, and excessive keratinization. Surface keratinization (hyperkeratosis), papillomatosis (papillary projections), or acanthosis (wide rete pegs) are common features of seborrheic keratosis. |
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