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vaccine
(redirected from live vaccine)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.07 sec.

vaccine

Any preparation of modified pathogens (viruses or bacteria) that is introduced into the body, usually either orally or by a hypodermic syringe, to induce the specific antibody reaction that produces immunity against a particular disease.

In 1796 Edward Jenner was the first to inoculate a child successfully with cowpox virus to produce immunity to smallpox. His method, the application of an infective agent to an abraded skin surface, is still used in smallpox inoculation.


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? Mentioned in ? References in periodicals archive
 
Interest in a potential attenuated live vaccine has been stimulated by the finding that targeted disruption of the Blastomyces dermatitidis gene, which encodes the surface adhesin BAD-l, renders the mutant avirulent.
The MMR vaccine, added to the vaccine schedule in 1979, is a live vaccine and does not contain a preservative.
Of the 9,000 doses of live vaccine shipped to the Los Angeles County Health Department, fewer than 100 public health workers have volunteered to be immunized - and just 10 employees at Santa Clarita's only hospital.
 
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