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interferon
(redirected from Peginterferon)

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interferon

Naturally occurring cellular protein that makes up part of mammalian defences against viral disease. Three types (alpha, beta, and gamma) are produced by infected cells and enter the bloodstream and uninfected cells, making them immune to virus attack.

Interferon was discovered in 1957 by Scottish virologist Alick Isaacs. Interferons are cytokines, small molecules that carry signals from one cell to another. They can be divided into two main types: type I (alpha, beta, tau, and omega) interferons are more effective at bolstering cells' ability to resist infection; type II (gamma) interferon is more important to the normal functioning of the immune system. Alpha interferon may be used to treat some cancers; interferon beta 1b has been found useful in the treatment of multiple sclerosis.



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MPH, from the National Cancer Institute (NCI), included 766 participants who had hepatitis C-related bridging fibrosis or cirrhosis and failed to respond to standard treatment of the anti-viral drugs peginterferon and ribavirin.
McHutchison and his colleagues randomly assigned 250 hepatitis C patients to get the standard drugs ribavirin and peginterferon alfa-2a, with or without telaprevir.
These treatments involve use of peginterferon and strong antiviral medications.
 
 
 
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