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photodynamic therapy
(redirected from photochemotherapy)

   Also found in: Medical, Wikipedia 0.01 sec.

photodynamic therapy

In medicine, therapy used to destroy cancer cells by the action of bright light and oxygen. PDT involves two stages: first a photosensitizer (light sensitive chemical) is injected into the body, where it accumulates in the tumour; the patient is then exposed to a bright light source which the photosensitizer absorbs and transfers as light energy to oxygen molecules within the cells. The energized oxygen (singlet oxygen) then destroys the tumour cells. The treatment is most successful in tumours easily exposed to a light source, such as those on the skin or in the mouth. PDT can eradicate 90% of skin tumours if applied at an early stage.



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Boelen RE, Faber WR, Lambers JC, Cormane RH: Long-term follow-up of photochemotherapy in pityriasis lichenoides.
Phototherapy (ultraviolet B, UVB) and photochemotherapy (psoralent ultraviolet A, PUVA) are both used for widespread psoriasis.
Thus, our data support the view [29-31, 52] that in laser photochemotherapy the mild hyperthermia (around 44[degrees]C) produced by irradiation can enhance synergistically the HPD-photoinduced tumour eradication.
 
 
 
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