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primary

In presidential election campaigns in the USA, a statewide ballot in which voters indicate their candidate preferences for the two main parties. Held in 41 states, primaries begin with New Hampshire in February and continue until June; they operate under varying complex rules. Primaries are also held to choose candidates for other posts, such as Congressional seats.

Generally speaking, the number of votes received by a candidate governs the number of delegates who will vote for that person at the national conventions in July/August, when the final choice of candidate for both Democratic and Republican parties is made. Some delegates remain loyal to the last ballot, others make deals to benefit the state or local situation as the field of candidates narrows. Some primaries are ‘closed’, being restricted to actual members of the party, others are ‘open’ to any registered voter.



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The bacterial degradation of primary bile acids leads to the accumulation of secondary bile acids (such as lithocholic acid) that have demonstrated capacities to induce cell necrosis or to promote tumour activity during in vitro studies with animal models.
6) [FIGURE 1 OMITTED] Cholesterol is converted to the two primary bile acids in hepatocytes, including cholic acid (CA) and chenodeoxycholic acid (CDCA), via a cascade of 12 enzymatic reactions.
There, bacteria convert the so-called primary bile acids into smaller, secondary bile acids -- which increase the risk of colon cancer.
 
 
 
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