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retrovirus
(redirected from retroviral)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.01 sec.

retrovirus

Any of a family of viruses (Retroviridae) that contain RNA as genetic material and are able to produce DNA copies of their RNA genes, which they incorporate into the host genome.

The retrovirus is able to transcribe RNA into DNA with the help of an enzyme encoded in its genome, known as the reverse transcriptase (since the transfer of genetic information from DNA to RNA is known as transcription, and retroviruses do the reverse of this). Retroviruses were seen as a rare and exotic exception to the rules of biology, until in the late 1980s the agents causing AIDS and some forms of leukaemia were recognized to be retroviruses.

Retroviruses are used as vectors in genetic engineering, but they cannot be used to target specific sites on the chromosome. Instead they incorporate their genes at random sites.



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The most commonly used rapid HIV test often results in a false-negative during the earliest and most contagious stages of HIV infection, known as acute retroviral syndrome, or ARS, according to a pediatric infectious-disease specialist at Johns Hopkins Children's Center.
Health agencies have called for continued condom use, after the Swiss National AIDS Commission stated that HIV patients can safely engage in unprotected sex after taking six months of retroviral therapy to suppress the virus in blood.
Retroviral infection "was almost a cataclysmic event for ancestral chimps and gorillas,' Eichler says.
 
 
 
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