These consisted of a 10-min formic acid (98%) bath at room temperature, 20 min of hydrated autoclaving at 121[degrees]C (Prestige Medical, AES Laboratories, Blackburn Lane, UK), and digestion at 37[degrees]C with proteinase K (Roche Diagnostics, Meylan, France) at a concentration of 20 [micro]g/mL for 15 min, with an additional incubation with streptomycin sulfate at 8.

Pragmatic Materials, Solon, OH, Cincinnati District A February inspection of Pragmatic Materials, Solon, OH, found that the company had not conducted appropriate tests to support the expiration dates assigned to at least six active ingredients, including cromolyn sodium, gentamicin sulfate, nicotinamide adenine dinucleotide (NADH), oxytocin, polymyxin B sulfate and streptomycin sulfate, resulting in a four-item 483.

Of special interest was the discovery of the synergistic actions of ND-497 with neomycin sulfate, streptomycin sulfate or polymyxin B sulfate.