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vincristine

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vincristine

Alkaloid extracted from the blue periwinkle plant Vinca rosea. Developed as an anticancer agent, it has revolutionized the treatment of childhood acute leukaemias; it is also included in chemotherapy regimens for some lymphomas (cancers arising in the lymph tissues) and lung and breast cancers. Side effects, such as nerve damage and loss of hair, are severe but usually reversible.



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In follow-up tests, the researchers took nerve cells in culture and treated their axons with the chemotherapy drug vincristine.
Patients received two cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine), MOPP/ABV (mechlorethamine, vincristine, procarbazine, and prednisone), or other ABVD-like chemotherapy.
Therefore, AHCC is safe and unlikely to result in increased toxicity when used in combination with commonly used chemotherapeutic agents such as Cyclophosphamide, Ifosfamide, Paclitaxel, Docetaxel, Irinotecan, Vincristine, interferon and Imatinib.
 
 
 
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